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Midea
Midea

Elevate your kitchen’s functionality and style with the Midea MDRD168FGE01 Undercounter Larder. This sleek 55.3cm freestanding appliance is not just a space-saver but also an energy-efficient ally capacity, divided into a 97L refrigeration and a 16L ice box, caters to all your storage needs. Organize with ease thanks to transparent drawers, illuminate your culinary treasures with an interior li of the tempered glass shelf. Plus, the reversible door design ensures this larder fits seamlessly into any kitchen layout. With a 4-star freezer rating, rest assured that your frozen goods are kept i

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Altaro VM Backup for VMware - Unlimited Plus Edition
Altaro VM Backup for VMware - Unlimited Plus Edition

Backup virtual machines for VMware Complete control over your VMware backup jobs on all hosts Simple but powerful features A backup and replication solution for VMware needs to be flexible and powerful so you can be confident in your backup strategy. You need to be able to replicate data to external storage or removable media, restore individual files or emails, restore to different points in time, verify backup integrity and downtime, etc. Above all, you need a solution with these capabilities: Eliminates the complexity of VMware and allows you to easily manage backups and quick restores. Handles complicated configurations and allows you to manage and monitor backups of all VMware hosts in a single view. Allows you to drag and drop VMs to a defined schedule and retention policy Instantly restore an email with a few mouse clicks Configure automatic backup scanning so you can sleep soundly Support multiple cloud storage providers: With full native integration with MS Azure, Amazon S3 and Wasabi, Altaro VM Backup allows you to conveniently store backups with the cloud provider of your choice. Advanced inline deduplication - the best deduplication in the industry! Fast, reliable backups and restores for VMware VMs Support for multiple hypervisors Altaro VM Backup supports both VMware and Microsoft Hyper-V, all from a single console. Simple. Let's go It only takes 15 minutes to get started with Altaro VM Backup. Simply run the installation wizard, select the hosts whose virtual machines you want to back up, and you're ready to start your first backup. Get to know Altaro VM Backup Back up your VMware across multiple devices and locations, both locally and over an internet connection to external storage. Back up Microsoft Hyper-V VMs too Use drive rotation for physically removable media Back up your live VMs without interruption, set advanced compression for your VM backups, and enable 256-bit AES encryption for securely stored backups. Set flexible backup retention policies for individual VMs. Restore individual files and emails instantly or restore an entire VM FAST. Restore to another VMware host and restore older backup versions, clones, etc. WAN-optimised replication: VMs can be continuously replicated to a remote site to significantly improve RTO (Recovery Time Objective). Most powerful and affordable VMware backup solution Ease of use and an affordable price don't mean you have to settle for limited functionality. Altaro VM Backup fully supports VMware vCenter and allows you to restore individual files and share emails directly from your VM backup. It is designed for scalability and allows you to easily access, manage and monitor multiple VMware hosts in a single window. There is no need to log in to individual hosts. Built-in host-level parallelisation for high performance when backing up multiple hosts across multiple hosts. Monitor and manage all your Altaro VM Backup installations from one cloud-based console. Learn more Robust features that help you create a solid backup strategy for all your VMware hosts Billing per host, not per CPU/socket/VM Free for 2 VMs per host, no time limit - our way of supporting micro-businesses. Supported operating systems VMware vCenter 5.0, 5.1, 5.5, 6.0, 6.5, 6.7 and 7.0 VMware vSphere 5.0, 5.1, 5.5, 6.0, 6.5, 6.7 and 7.0 VMware ESXi 5.0, 5.1, 5.5, 6.0, 6.5, 6.7 and 7.0 (The free VMware ESXi is not supported) Also supported Windows Server 2019 Windows Server 2016 Windows Server 2012 R2 Windows Server 2012 Windows Server 2008 R2 Windows Hyper-V Server (basic installation) Dependencies None No SQL required No additional Windows licences required

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Love Pride Flag male t-shirt.
Love Pride Flag male t-shirt.

Support Pride with this cool Love Pride flag design!

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This Image Is Not Available In Your Country mug.
This Image Is Not Available In Your Country mug.

Cannot see this t-shirt design? Maybe you're trying to read it in the wrong country.

Price: 14.95 € | Shipping*: Free €

How do epigenetic changes enter the germline?

Epigenetic changes can enter the germline through a process called epigenetic inheritance. This can occur when epigenetic modifica...

Epigenetic changes can enter the germline through a process called epigenetic inheritance. This can occur when epigenetic modifications, such as DNA methylation or histone modifications, are present in the germ cells (sperm and egg cells) and are passed on to the next generation. These changes can be maintained during cell division in the germline and can influence gene expression in the offspring. Additionally, environmental factors and lifestyle choices can also impact epigenetic changes in the germline, potentially affecting future generations.

Source: AI generated from FAQ.net

Keywords: Sperm Oocyte Methylation Histones Gametes Inheritance Transgenerational DNA Environment Imprinting

What is the mechanism of epigenetic changes?

Epigenetic changes occur through modifications to the structure of DNA and the proteins associated with it, rather than changes to...

Epigenetic changes occur through modifications to the structure of DNA and the proteins associated with it, rather than changes to the DNA sequence itself. These modifications can include DNA methylation, histone modification, and non-coding RNA regulation. DNA methylation involves the addition of a methyl group to the DNA molecule, which can affect gene expression. Histone modification involves changes to the proteins around which DNA is wound, altering the accessibility of the DNA for gene expression. Non-coding RNA can also regulate gene expression by interacting with DNA and proteins. These epigenetic changes can result in alterations to gene expression patterns without changing the underlying DNA sequence.

Source: AI generated from FAQ.net

Are epigenetic patterns inherited between generations in humans?

Epigenetic patterns can be inherited between generations in humans. Research has shown that certain epigenetic marks, such as DNA...

Epigenetic patterns can be inherited between generations in humans. Research has shown that certain epigenetic marks, such as DNA methylation and histone modifications, can be passed down from parents to offspring. These inherited epigenetic patterns can influence gene expression and potentially contribute to the inheritance of certain traits and diseases. However, the extent to which epigenetic inheritance occurs and its impact on human health and development is still an active area of research.

Source: AI generated from FAQ.net
Snickers 6923 Mens Flexiwork Floorlayers Work Holster Pocket Trousers Grey 41" 37"
Snickers 6923 Mens Flexiwork Floorlayers Work Holster Pocket Trousers Grey 41" 37"

Floorlayer work trousers with durable knee protection designed for work that includes long hours on the knees. The trousers are made of 4-way mechanical stretch ripstop fabric and features CORDURA® reinforcements as well as 4-way stretch Armortex® Kevlar® fiber by DuPontTM at the knees for optimal durability, protection and ease of movement. Adjustable leg endings ensure flexibility while leg knife pocket and ruler pocket offer practical storage on the go. Features and Benefits • Ripstop fabric with 4-way mechanical stretch • Full stretch Armortex® Kevlar® fiber by DuPontTM at the knees • Reinforced with durable CORDURA® fabric • Certified floor layer knee pockets standard EN14404 • Adjustable leg endings • Integrated yet detachable hardwearing belt with easy-to-close durable polyamide buckle for superior waist fit and comfort Innovation: This product has a Registered Community Design (RCD), or national design registrations. Available in Sizes: 44-64, 88-124, 146-162, 192-212, 250-258 Materials: Main: 65% polyester, 35% cotton, 225 g/m2. Reinforcement 1: Armortex® 56% polyamide, 26% elastane, 18% DuPont™ Kevlar® aramid fibers.Reinforcement 2: 100% polyamide CORDURA®, 205 g/m². Certification: EN 14404 - Knee protection

Price: 143.95 € | Shipping*: 5.95 €
Snickers 6923 Mens Flexiwork Floorlayers Work Holster Pocket Trousers Grey 38" 32"
Snickers 6923 Mens Flexiwork Floorlayers Work Holster Pocket Trousers Grey 38" 32"

Floorlayer work trousers with durable knee protection designed for work that includes long hours on the knees. The trousers are made of 4-way mechanical stretch ripstop fabric and features CORDURA® reinforcements as well as 4-way stretch Armortex® Kevlar® fiber by DuPontTM at the knees for optimal durability, protection and ease of movement. Adjustable leg endings ensure flexibility while leg knife pocket and ruler pocket offer practical storage on the go. Features and Benefits • Ripstop fabric with 4-way mechanical stretch • Full stretch Armortex® Kevlar® fiber by DuPontTM at the knees • Reinforced with durable CORDURA® fabric • Certified floor layer knee pockets standard EN14404 • Adjustable leg endings • Integrated yet detachable hardwearing belt with easy-to-close durable polyamide buckle for superior waist fit and comfort Innovation: This product has a Registered Community Design (RCD), or national design registrations. Available in Sizes: 44-64, 88-124, 146-162, 192-212, 250-258 Materials: Main: 65% polyester, 35% cotton, 225 g/m2. Reinforcement 1: Armortex® 56% polyamide, 26% elastane, 18% DuPont™ Kevlar® aramid fibers.Reinforcement 2: 100% polyamide CORDURA®, 205 g/m². Certification: EN 14404 - Knee protection

Price: 143.95 € | Shipping*: 5.95 €
Microsoft Windows Server 2016 Standard additional license Core AddOn
Microsoft Windows Server 2016 Standard additional license Core AddOn

New features in Windows Server 2016 Licensing In terms of licensing, a lot has changed compared to the previous versions. With Windows Server 2016, this is no longer done processor-based, but core-based. Please note the following: Each processor must be licensed with at least 8 cores Each server must be licensed with at least 16 cores. With Windows Server 2016 Standard Licenses, you receive two licenses for Windows Server instances for each complete licensing of the hardware. This article is an additional license for 4 processor cores under Windows Server 2016 Standard. The basic license for 16 or 24 cores is required as a basis. Overview of functions: Additional security levels Improve security in your server structure and reduce risk with multiple integrated layers of protection New deployment options Improve availability and reduce resource utilization with the slim Nano Server. Integrated containers Windows Server and Hyper-V containers enable flexible development and management. Cost-efficient storage Create a highly available and scalable software-defined memory and save costs Innovative networks Use software-defined networks for automation with cloud-like efficiency. The most important innovations in detail: General Physical and virtual machines benefit from improved time accuracy through improvements in the Win32 time service and Hyper-V time synchronization service. Windows Server can now be used to host services that comply with future regulations that require 1 ms UTC accuracy. nano server Innovations in Nano Server. Nano Server now has an updated module for creating Nano Server images. In addition, there is greater separation of functionality for physical hosts and guest VMs, and you benefit from support for different editions of Windows Server. The Recovery Console has also been improved. These improvements include the separation of inbound and outbound firewall rules and the ability to repair WinRM configuration. remote desktop services With a highly available RDS deployment, you can use Azure SQL database for your remote desktop connection broker in high availability mode. Identity and access New identity features enhance the ability to protect Active Directory environments. In addition, organizations can migrate to cloud-only or hybrid deployments where some applications and services are hosted in the cloud and others are hosted locally. Management and automation Management and Automation focuses on tool and reference information for IT professionals who want to run and manage Windows Server 2016 (including Windows PowerShell). Windows PowerShell 5.0 includes important new features-including support for class development and new security features-that extend the functionality, improve the user experience, and make it easier and more powerful to control and manage Windows-based environments. See Windows Management Framework (WMF) 5.0 RTM Release Notes Overview for details. The new features for Windows Server 2016 include the following: PowerShell.exe can run locally on Nano Server (not just remotely), new cmdlets for local users and groups replace the GUI, new PowerShell debugging support, and new support in Nano Server for security logging and auditing and JEA. Software defined networks You can now both mirror traffic and route it to new or existing virtual Devices. Combined with a distributed firewall and network security groups, you can dynamically segment and protect workloads in a similar way to Azure. You can also deploy and manage the entire software-defined network stack using System Center Virtual Machine Manager. And you can use Docker to manage Windows Server container networks and assign SDN policies not only to virtual machines but also to containers. For more information, see Plan Software Defined Networking Deployment. TCP performance improvementsThe default Initial Congestion Window (ICW) has been increased from 4 to 10 and TCP Fast Open (TFO) has been implemented . TFO reduces the time required to establish a TCP connection, and the increased ICW allows larger objects to be transferred in the initial burst. This combination can significantly reduce the time required to transfer an Internet object between the client and the cloud. To improve TCP behavior during recovery after packet loss, TCP: Tail Loss Probe (TLP) and Recent ACKnowledgement (RACK) have been implemented. TLP helps convert RTOs (Retransmit TimeOuts) to fast recoveries, and RACK reduces the time it takes for fast recovery to retransmit a lost packet. Scope of delivery: - Additional license add-on - invoice in your name incl. VAT - Instructions for easy installation. Note: This offer does not include a product key sticker (COA label) This offer is aimed at private individuals as well as companies, business customers, authorities, organisations, schools, communities and churches.

Price: 210.72 £ | Shipping*: 0.00 £
Festive 60cm Gingerbread Man Infinity Light
Festive 60cm Gingerbread Man Infinity Light

Step into a world of holiday magic with the 60cm Infinity Gingerbread Man, a whimsical decoration that brings festive joy to any space. Dressed in a classic Santa hat and holding a cheerful candy cane, this charming gingerbread man is a delightful blend of tradition and modern style, designed to captivate hearts and light up your home.Crafted in warm brown tones with accents of white and red, this gingerbread man isnt just a decorationhes a symbol of the holiday spirit, inviting everyone to share in the festive cheer. His sturdy wooden base ensures he stands proudly wherever you place him, whether welcoming guests in the entryway, adding a touch of fun to your living room, or becoming the centerpiece of your holiday display.But the magic doesnt end there. The infinity lighting effect creates an enchanting illusion of endless depth, making it seem as though the gingerbread man is glowing from within. This mesmerizing effect adds a layer of wonder to your holiday décor, making this piece not only a festive decoration but a conversation starter and a source of endless holiday delight.With a generous 3-metre lead length, this gingerbread man offers plenty of flexibility in placement, allowing you to easily incorporate him into your holiday display, whether indoors or near a sheltered outdoor space. His festive colours and playful design make him a perfect addition to any Christmas scene, bringing a smile to the faces of all who see him.Celebrate the season with the 60cm Infinity Gingerbread Man, and let his warm glow and joyful presence fill your home with holiday magic.

Price: 36.13 € | Shipping*: 0.00 €
Raaco Carrymore Storage System Trolley
Raaco Carrymore Storage System Trolley

The Raaco CarryMore Storage System Trolley is a folding transport solution designed specifically for moving multiple CarryMore storage units efficiently. This purpose-built trolley integrates seamlessly with the Raaco CarryMore system, allowing tradespeople to transport an entire stack of organiser units in one trip. Constructed with an ergonomic handle and large wheels, the trolley ensures comfortable manoeuvrability across workshop floors, construction sites and van-to-job transitions. The folding base design maximises space efficiency during storage and transportation, whilst magnetic fixings hold the trolley securely in its upright position during use. This storage trolley is ideal for mobile tradespeople who need organised access to multiple component boxes or fixings on site. It's particularly suited to electricians, plumbers and maintenance contractors who rely on the CarryMore system for sorting and transporting small parts, fasteners and accessories between locations. Features and Benefits: • Ergonomic handle provides comfortable grip during transport • Large wheels enable smooth movement over uneven surfaces • Folding base with magnetic fixings for compact storage • Compatible with multiple stacked CarryMore units Specifications: Truck Type: Folding

Price: 301.95 € | Shipping*: 5.95 €
Samsung
Samsung

Bespoke AI™ 11kg Washing Machine Series 5+ with ecobubble™ and SpaceMax™ ecobubble™ technology is one of our brilliantly useful features designed to make laundry less of a chore. Mixing air, w creates bubbles that wash your clothes at cooler temperatures, helping you to bring down your energy bills. Spacemax - Get the same footprint washing machine but with an extra 2kg drum inside! Thanks our washing machine now holds a large drum boasting a whooping 11kg capacity while the outside dimensions stays the same. Intelligent washing - AI Control, Wash laundry easily and effectively with AI remembering your habits, suggesting cycles* and displaying timely information. The SmartThings App** offers advice on cycles, planning and troubleshooting. And it selects the ideal drying course for a more than just stains and odours. The Hygiene Steam cycle on your Samsung washing machine releases hot steam, eliminating 99.9% of bacteria and inactivating allergens Digital Inverter Technology - A q to last, economical and has the added peace of mind of a 20 year warranty. It’s all possible with Digital Inverter Technology. SmartThings Home Life - Washing just got smarter. With an intelligent, Samsung smart washing machine remembers your family’s laundry habits and suggests your favourite cycles first. From whites to bed change days, track every cycle’s progress on the simply designed done, you’ll get a notification on your phone with the SmartThings app*. Want to make things even simpler? Use the app* to schedule your washes and get guides to find the perfect setting. Say goodb drawer with your washing machine. The StayClean Drawer rinses it all away for you. With no soap build up, your detergent flows more freely into the drum for a cleaner, fresher wash. Looking for the a sparkling washing machine. Drum Clean keeps the inside of your washer hygienically clean with a combination of soaking, pulsating and high-speed spinning that removes 99.9% of odour-causing bacteria Bespoke AI™ 11kg Washing Machine Series 5+ with ecobubble™ and SpaceMax™ ecobubble™ technology is one of our brilliantly useful features designed to make laundry less of a chore. Mixing air, w

Price: 574.00 £ | Shipping*: 0 £
Ada Nursery Wardrobe White Ash | 2 Removable Hanging Rails | 180cm H
Ada Nursery Wardrobe White Ash | 2 Removable Hanging Rails | 180cm H

Item Description: Adaptable Storage for Your Growing Child The Ada Nursery Wardrobe combines modern design with practical functionality. Featuring a soft white and ash finish with brushed metal handles, this double wardrobe offers versatile storage that transitions seamlessly from nursery to toddler room, adapting to your child's changing needs. Key Features: • Convertible Interior - Two removable hanging rails allow conversion to full-length hanging space • Modern Design - Clean lines with white and ash finish complement any nursery decor • Quality Details - Brushed metal handles add contemporary sophistication • Spacious Storage - Multiple configuration options for optimal organization • Adaptable Solution - Grows with your child from infancy through toddler years Specifications: Colour: White Ash Material: Engineered Wood Dimensions: 180cm (H) x 87cm (W) x 49cm (D) Interior: 2 Removable Hanging Rails + 1 Fixed Shelf Assembly: Self-Assembly Required Style: Modern Classic Smart Storage Features This wardrobe provides intelligent organization solutions: Dual hanging rails perfect for infant clothing and accessories Adjustable configuration adapts to growing storage needs Generous shelf space for folded items and nursery essentials Compact depth ideal for smaller nursery spaces Why Choose This Nursery Wardrobe? The Ada Wardrobe offers exceptional versatility with its convertible design that serves from infancy through preschool years. The neutral colour scheme and contemporary styling ensure it remains a functional and attractive piece as your child grows, while the quality construction guarantees lasting durability. Ideal For: Nursery organization and storage Small bedroom spaces Parents seeking adaptable furniture solutions Modern and traditional decor schemes Ready to Organize Your Nursery? Add to cart now to secure this versatile storage solution. The compact 49cm depth makes it ideal for smaller rooms while providing ample storage capacity. We recommend verifying your space measurements before purchase to ensure perfect placement. Thank you for your interest in our nursery collection.

Price: 234.99 € | Shipping*: 0.00 €
Perfume Making Workshop in Dorset
Perfume Making Workshop in Dorset

Perfume Making Experience Days: Create the perfect scent during this 2 hour 30 minute perfume making workshop. You'll work with an expert instructor to craft your signature scent, and learn all about how perfume is really made! At the end of your workshop, you'll have a bottle to take home with you. Arriving at the incredible grounds at Keyneston Mill in Dorset, you'll be struck by the incredible natural beauty of the area. Before your class you are welcome to explore the botanical gardens, which have been featured on BBC Gardeners' World. Keyneston Mill is the creative home of Parterre Fragrances where they grow, harvest and distil unusual plants and ingredients for their luxury perfumes. You will be met by the fantastic, friendly team who will guide you through the perfume making workshop. Whether you are a beginner or have previously created perfumes, this workshop is perfect for anyone. This perfume making workshop will give you the opportunity to discover the scents you love and turn them into a beautiful perfume with essential oils! We all have our favourite scents that we regularly wear whether it be fruity, floral, spicy or citrus that suits our style. Expert perfume-maker Julia Bridger will guide you through the workshop as you design and blend your very own perfume. At the end of the session, you will go away with a 50 ml bottle of perfume that you designed and blended together, representative of your own style and individuality. This perfume making workshop would make the perfect experience day for Mother's Day, a hen do or a birthday party!

Price: 93 £ | Shipping*: £

* All prices are inclusive of the statutory value added tax and, if applicable, plus shipping costs. The offer information is based on the information provided by the respective shop and is updated by automated processes. A real-time update does not take place, so that there may be deviations in individual cases.